The Epic Collection series featuring the wacky team-ups of Spider-Man and Deadpool continues! Nobody does slapstick like Spidey and Deadpool do slapstick! Except maybe... Slapstick? But the walking cartoon has terrible comic timing, showing up exactly when Wade Wilson and Peter Parker have declared: no more jokes! Then, when Spider-Man learns that Deadpool is selling S.H.I.E.L.D. tech on the black market, it's the last straw: team-up over!

The ensuing battle takes them across the Marvel Universe, and climaxes in a face-off with the leveled-up Chameleon! But as disaster strikes across two eras, get ready to meet Old Men Parker and Wilson! Timelines are about to collide, courtesy of Clonepool! But who is he, what is he, and where did he come from? Plus: Deadpool's marital problems spell domestic trouble for him, Spider-Man and the Mercs for Money!