God created man. Man created immortality.

Billionaire industrialist Damian Hale (Ben Kingsley) has long been a master of his universe, excelling at power plays from his NYC base of operations. Estranged from his activist daughter Claire (Michelle Dockery), Damian's only real connection is with his lifelong friend and right-hand man Martin O'Neil (Victor Garber). But a dire cancer diagnosis makes Damian determined to access a radical medical procedure, "shedding" that will turn back the clock for him. The process is offered to Damian by Albright (Matthew Goode), the brilliant head of a secret organization that caters to the wealthy. Damian seizes the opportunity, and his death is staged. The world now thinks he is gone, but he is in fact "shedding" his consciousness is being transferred into the body of a healthy man (Ryan Reynolds) decades younger than he. The operation is deemed a success. Adapting to his new physical form and beginning a second life in New Orleans, Damian is befriended by a local man, Anton (Derek Luke). Both preserving his newfound health and indulging himself, Damian becomes comfortable in his new identity as "Edward". But the disturbing images flooding his consciousness are not easily explained away by Albright's contention that immortality has some side effects. When he finds himself drawn to single mother Madeline (Natalie Martinez), Damian starts to uncover the mystery of Edward's origin - and those who will kill to protect the organization. Summoning two lifetimes' worth of strength and resourcefulness, Damian fights for his life and for the lives that he has impacted.