Ichise grief only allows him to enjoy the pain of the fighting pits in the underground city of Lukuss. However, when a gang punishes Ichise by cutting his arm and leg off, his will to live overcomes the odds and attracts the attention of the ruling Organo syndicate that controls the cybernetic Texhnolyze technology that they usually reserve for the elite. Meanwhile, an outsider has come down to the city and, along with a young psychic girl, the dominos are beginning to fall in the seething unrest of the city as their paths slowly intertwine with Ichise.